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Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin

Long ncRNAs are often enriched in the nucleus and at chromatin, but whether their dissociation from chromatin is important for their role in transcription regulation is unclear. Here, we group long ncRNAs using epigenetic marks, expression and strength of chromosomal interactions; we find that long...

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Detalles Bibliográficos
Autores principales: Ntini, Evgenia, Louloupi, Annita, Liz, Julia, Muino, Jose M., Marsico, Annalisa, Ørom, Ulf Andersson Vang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915440/
https://www.ncbi.nlm.nih.gov/pubmed/29691407
http://dx.doi.org/10.1038/s41467-018-04100-3