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Metabolic implications of hypoxia and pseudohypoxia in pheochromocytoma and paraganglioma
Hypoxia is a critical driver of cancer pathogenesis, directly inducing malignant phenotypes such as epithelial-mesenchymal transition, stem cell-like characteristics and metabolic transformation. However, hypoxia-associated phenotypes are often observed in cancer in the absence of hypoxia, a phenoty...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915505/ https://www.ncbi.nlm.nih.gov/pubmed/29450727 http://dx.doi.org/10.1007/s00441-018-2801-6 |