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Immunosilencing peptides by stereochemical inversion and sequence reversal: retro-D-peptides

Peptides are experiencing a new era in medical research, finding applications ranging from therapeutics to vaccines. In spite of the promising properties of peptide pharmaceuticals, their development continues to be hindered by three weaknesses intrinsic to their structure, namely protease sensitivi...

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Detalles Bibliográficos
Autores principales: Arranz-Gibert, Pol, Ciudad, Sonia, Seco, Jesús, García, Jesús, Giralt, Ernest, Teixidó, Meritxell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915530/
https://www.ncbi.nlm.nih.gov/pubmed/29691418
http://dx.doi.org/10.1038/s41598-018-24517-6