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Using a Vancomycin PBPK Model in Special Populations to Elucidate Case‐Based Clinical PK Observations

Simultaneous changes in several physiological factors may contribute to the large pharmacokinetic (PK) variability of vancomycin. This study was designed to systematically characterize the effects of multiple physiological factors to the altered PK of vancomycin observed in special populations. A va...

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Detalles Bibliográficos
Autores principales: Emoto, Chie, Johnson, Trevor N., McPhail, Brooks T., Vinks, Alexander A., Fukuda, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915605/
https://www.ncbi.nlm.nih.gov/pubmed/29446256
http://dx.doi.org/10.1002/psp4.12279