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Protein methyltransferase inhibitors as precision cancer therapeutics: a decade of discovery
The protein methyltransferases (PMTs) represent a large class of enzymes that catalyse the methylation of side chain nitrogen atoms of the amino acids lysine or arginine at specific locations along the primary sequence of target proteins. These enzymes play a key role in the spatio-temporal control...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Royal Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915721/ https://www.ncbi.nlm.nih.gov/pubmed/29685962 http://dx.doi.org/10.1098/rstb.2017.0080 |