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Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC

Fusobacterium nucleatum is a key member of the human oral biofilm. It is also implicated in preterm birth and colorectal cancer. To facilitate basic studies of fusobacterial virulence, we describe here a versatile transposon mutagenesis procedure and a pilot screen for mutants defective in biofilm f...

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Detalles Bibliográficos
Autores principales: Wu, Chenggang, Al Mamun, Abu Amar Mohamed, Luong, Truc Thanh, Hu, Bo, Gu, Jianhua, Lee, Ju Huck, D’Amore, Melissa, Das, Asis, Ton-That, Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915739/
https://www.ncbi.nlm.nih.gov/pubmed/29691334
http://dx.doi.org/10.1128/mBio.00360-18