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Access to benzo-fused nine-membered heterocyclic alkenes with a trifluoromethyl carbinol moiety via a double decarboxylative formal ring-expansion process under palladium catalysis

Direct access to pharmaceutically attractive benzo-fused nine-membered heterocyclic alkenes 3 with a trifluoromethyl carbinol moiety was achieved via a palladium-catalyzed double-decarboxylative formal ring-expansion process from six-membered trifluoromethyl benzo[d][1,3]oxazinones 1 to nine-membere...

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Detalles Bibliográficos
Autores principales: Das, Pulakesh, Gondo, Satoshi, Nagender, Punna, Uno, Hiroto, Tokunaga, Etsuko, Shibata, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915791/
https://www.ncbi.nlm.nih.gov/pubmed/29732106
http://dx.doi.org/10.1039/c7sc05447e