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Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake

Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC) respond to numerous hormonal and neural signals, resulting in changes in food intake. Here, we demonstrate that ARC POMC neurons express capsaicin-sensitive transient receptor potential vanilloid 1 receptor (TRPV1)-l...

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Detalles Bibliográficos
Autores principales: Jeong, Jae Hoon, Lee, Dong Kun, Liu, Shun-Mei, Chua, Streamson C., Schwartz, Gary J., Jo, Young-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915833/
https://www.ncbi.nlm.nih.gov/pubmed/29689050
http://dx.doi.org/10.1371/journal.pbio.2004399