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Activation of Hepatic Stellate Cells During Liver Carcinogenesis Requires Fibrinogen/Integrin αvβ5 in Zebrafish

Hepatocellular carcinoma (HCC) is one of the most common cancers and it usually develops from a background of liver fibrosis or inflammation. The crosstalk between tumor cells and stromal cells plays an important and stimulating role during tumor progression. Previously we found in a kras(V12)–induc...

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Detalles Bibliográficos
Autores principales: Yan, Chuan, Yang, Qiqi, Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915969/
https://www.ncbi.nlm.nih.gov/pubmed/29649779
http://dx.doi.org/10.1016/j.neo.2018.02.002