Cargando…

POH1 Knockdown Induces Cancer Cell Apoptosis via p53 and Bim()()()()()

The ubiquitin-proteasome system is implicated in cell apoptosis that is frequently dysregulated in human cancers. POH1/rpn11/PSMD14, as a part of the 19S proteasomal subunit, contributes to the progression of malignancy, but its role in apoptosis remains unclear. Here, we showed that POH1 expression...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Chun-Hua, Lu, Shi-Xun, Liu, Li-Li, Li, Yong, Yang, Xia, He, Yang-Fan, Chen, Shi-Lu, Cai, Shao-Hang, Wang, Hong, Yun, Jing-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915990/
https://www.ncbi.nlm.nih.gov/pubmed/29573636
http://dx.doi.org/10.1016/j.neo.2018.02.005