Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I

Macroautophagy is a conserved eukaryotic process for degradation of cellular components in response to lack of nutrients. It is involved in the development of diseases, notably cancer and neurological disorders including Parkinson's disease. Small molecule autophagy modulators have proven to be...

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Detalles Bibliográficos
Autores principales: Robke, Lucas, Futamura, Yushi, Konstantinidis, Georgios, Wilke, Julian, Aono, Harumi, Mahmoud, Zhwan, Watanabe, Nobumoto, Wu, Yao-Wen, Osada, Hiroyuki, Laraia, Luca, Waldmann, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916016/
https://www.ncbi.nlm.nih.gov/pubmed/29732085
http://dx.doi.org/10.1039/c7sc05040b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916016/
https://www.ncbi.nlm.nih.gov/pubmed/29732085
http://dx.doi.org/10.1039/c7sc05040b

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