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A Pre-Clinical Assessment of the Pan-ERBB Inhibitor Dacomitinib in Pediatric and Adult Brain Tumors

Glioblastoma in adults, and medulloblastoma and pineoblastoma that mainly affect children, are aggressive brain tumors. The survival for patients with glioblastoma remains dismal. While the cure rate for medulloblastoma exceeds 70%, this figure has stagnated over the past few decades and survivors s...

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Detalles Bibliográficos
Autores principales: Endersby, Raelene, Whitehouse, Jacqueline, Hii, Hilary, Greenall, Sameer A., Johns, Terrance G., Gottardo, Nicholas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916087/
https://www.ncbi.nlm.nih.gov/pubmed/29574250
http://dx.doi.org/10.1016/j.neo.2018.02.004