The Sineoculis Homeobox Homolog 1 (SIX1) Gene Regulates Paclitaxel Resistance by Affecting Reactive Oxygen Species and Autophagy in Human Hepatocellular Carcinoma Cell Line HepG2

BACKGROUND: The objective of this study was to explore the role of SIX1 in paclitaxel (TAX) resistance of HepG2 cells via reactive oxygen species (ROS) and autophagy pathway. MATERIAL/METHODS: Hepatoma cell line HepG2 was treated with SIX1 knockdown or/and TAX. Cell growth was detected by MTT assay...

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Detalles Bibliográficos
Autores principales: Li, Baowei, Zhao, Shahe, Geng, Ruipeng, Huo, Zhongchao, Zhang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916092/
https://www.ncbi.nlm.nih.gov/pubmed/29656300
http://dx.doi.org/10.12659/MSM.906361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916092/
https://www.ncbi.nlm.nih.gov/pubmed/29656300
http://dx.doi.org/10.12659/MSM.906361

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