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Cardiac myosin activators for heart failure therapy: focus on omecamtiv mecarbil

Heart failure continues to be a major global health problem with a pronounced impact on morbidity and mortality and very limited drug treatment options especially with regard to inotropic therapy. Omecamtiv mecarbil is a first-in-class cardiac myosin activator, which increases the proportion of myos...

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Detalles Bibliográficos
Autores principales: Kaplinsky, Edgardo, Mallarkey, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioExcel Publishing Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916097/
https://www.ncbi.nlm.nih.gov/pubmed/29707029
http://dx.doi.org/10.7573/dic.212518