High-throughput identification of G protein-coupled receptor modulators through affinity mass spectrometry screening

G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins and thus constitute an important family of therapeutic targets. Therefore, significant effort has been put towards the identification of novel ligands that can modulate the activity of a GPCR target with high ef...

Descripción completa

Detalles Bibliográficos
Autores principales: Qin, Shanshan, Meng, Mengmeng, Yang, Dehua, Bai, Wenwen, Lu, Yan, Peng, Yao, Song, Gaojie, Wu, Yiran, Zhou, Qingtong, Zhao, Suwen, Huang, Xiping, McCorvy, John D., Cai, Xiaoqing, Dai, Antao, Roth, Bryan L., Hanson, Michael A., Liu, Zhi-Jie, Wang, Ming-Wei, Stevens, Raymond C., Shui, Wenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916221/
https://www.ncbi.nlm.nih.gov/pubmed/29732102
http://dx.doi.org/10.1039/c7sc04698g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916221/
https://www.ncbi.nlm.nih.gov/pubmed/29732102
http://dx.doi.org/10.1039/c7sc04698g

Ejemplares similares