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Rapid access to diverse, trifluoromethyl-substituted alkenes using complementary strategies

Two synergistic approaches to the facile assembly of complex α-trifluoromethyl alkenes are described. Using α-trifluoromethyl-β-silyl alcohols as masked trifluoromethyl alkenes, cross-coupling or related functionalization processes at distal electrophilic sites can be executed without inducing Peter...

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Detalles Bibliográficos
Autores principales: Phelan, James P., Wiles, Rebecca J., Lang, Simon B., Kelly, Christopher B., Molander, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916225/
https://www.ncbi.nlm.nih.gov/pubmed/29732105
http://dx.doi.org/10.1039/c7sc05420c