PTEN deficiency promotes pathological vascular remodeling of human coronary arteries

Phosphatase and tensin homolog (PTEN) is an essential regulator of the differentiated vascular smooth muscle cell (SMC) phenotype. Our goal was to establish that PTEN loss promotes SMC dedifferentiation and pathological vascular remodeling in human atherosclerotic coronary arteries and nonatheroscle...

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Detalles Bibliográficos
Autores principales: Moulton, Karen S., Li, Marcella, Strand, Keith, Burgett, Shawna, McClatchey, Penn, Tucker, Rebecca, Furgeson, Seth B., Lu, Sizhao, Kirkpatrick, Bruce, Cleveland, Joseph C., Nemenoff, Raphael A., Ambardekar, Amrut V., Weiser-Evans, Mary C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916252/
https://www.ncbi.nlm.nih.gov/pubmed/29467331
http://dx.doi.org/10.1172/jci.insight.97228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916252/
https://www.ncbi.nlm.nih.gov/pubmed/29467331
http://dx.doi.org/10.1172/jci.insight.97228

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