Cargando…

PTEN deficiency promotes pathological vascular remodeling of human coronary arteries

Phosphatase and tensin homolog (PTEN) is an essential regulator of the differentiated vascular smooth muscle cell (SMC) phenotype. Our goal was to establish that PTEN loss promotes SMC dedifferentiation and pathological vascular remodeling in human atherosclerotic coronary arteries and nonatheroscle...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moulton, Karen S., Li, Marcella, Strand, Keith, Burgett, Shawna, McClatchey, Penn, Tucker, Rebecca, Furgeson, Seth B., Lu, Sizhao, Kirkpatrick, Bruce, Cleveland, Joseph C., Nemenoff, Raphael A., Ambardekar, Amrut V., Weiser-Evans, Mary C.M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916252/ https://www.ncbi.nlm.nih.gov/pubmed/29467331 http://dx.doi.org/10.1172/jci.insight.97228

Ejemplares similares

4369 Reprogramming of vascular smooth muscle cells to multipotent progenitor cells contributes to progression of atherosclerosis
por: Dubner, Allison Milfred, et al.
Publicado: (2020)

Smooth muscle–derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis
por: Lu, Sizhao, et al.
Publicado: (2020)

Redistribution of the chromatin remodeler Brg1 directs smooth muscle–derived adventitial progenitor–to–myofibroblast differentiation and vascular fibrosis
por: Jolly, Austin J., et al.
Publicado: (2023)

Selective Inactivation of PTEN in Smooth Muscle Cells Synergizes With Hypoxia to Induce Severe Pulmonary Hypertension
por: Horita, Henrick, et al.
Publicado: (2013)

Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation
por: Horita, Henrick, et al.
Publicado: (2016)

Smooth muscle-derived adventitial progenitor cells promote key cell type transitions controlling plaque stability in atherosclerosis in a Klf4-dependent manner
por: Dubner, Allison M, et al.
Publicado: (2023)

Reduce, Reuse, Recycle…Unloading, Autophagy, and Myocardial Recovery
por: Ambardekar, Amrut V., et al.
Publicado: (2022)

CD8(+) T cells modulate autosomal dominant polycystic kidney disease progression
por: Kleczko, Emily K., et al.
Publicado: (2018)

Left Ventricular Assist Device Effects on Metabolic Substrates in the Failing Heart
por: Weitzel, Lindsay B., et al.
Publicado: (2013)

Assessment of Autophagy Markers Suggests Increased Activity Following LVAD Therapy
por: Martin, Thomas G., et al.
Publicado: (2023)

Facilitating Evolution during Design and Implementation
por: McClatchey, R
Publicado: (2015)

Minutes / Transparencies of DAQ Software meeting of 18 2 87
por: McClatchey, R
Publicado: (1987)

EPHecting cell contact by increasing cortical tension
por: McClatchey, Andrea I.
Publicado: (2021)

Anti- and Protumorigenic Effects of PPARγ in Lung Cancer Progression: A Double-Edged Sword
por: Li, Howard, et al.
Publicado: (2012)

3157 Relationship between abnormal nocturnal blood pressure patterns and end-organ damage following heart transplantation.
por: Oreschak, Kris, et al.
Publicado: (2019)

Healthgrid 2005 : From Grid to Healthgrid
por: Solomonides, Tony, et al.
Publicado: (2005)

Concomitant surgical cryoablation for refractory ventricular tachycardia and left ventricular assist device placement: a dual remedy but a recipe for thrombosis?
por: McIlvennan, Colleen K., et al.
Publicado: (2016)

Nf2/Merlin: a coordinator of receptor signalling and intercellular contact
por: Curto, M, et al.
Publicado: (2008)

Use of Software Engineering Techniques in the Design of the ALEPH Data Acquisition System
por: Harvey, J, et al.
Publicado: (1987)

Use of software engineering techniques in the design of the ALEPH data acquisition system
por: Charity, T, et al.
Publicado: (1987)

Refractive Growth of the Crystalline Lens in the Infant Aphakia Treatment Study
por: McClatchey, Thaddeus S., et al.
Publicado: (2022)

Activation and Molecular Targets of Peroxisome Proliferator-Activated Receptor-γ Ligands in Lung Cancer
por: Nemenoff, Raphael A., et al.
Publicado: (2008)

Role of the Phosphatase PTEN in Early Vascular Remodeling
por: Sedding, Daniel G., et al.
Publicado: (2013)

CICERO RD38: a distributed information system for HEP controls
por: Le Goff, J M, et al.
Publicado: (1995)

Data analysis with the DIANA meta-scheduling approach
por: Anjum, A, et al.
Publicado: (2008)

Towards Provenance and Traceability in CRISTAL for HEP
por: Shamdasani, Jetendr, et al.
Publicado: (2014)

Designing Reusable Systems that Can Handle Change: Description-Driven Systems : Revisiting Object-Oriented Principles
por: McClatchey, Richard, et al.
Publicado: (2014)

A Description Driven Approach for Flexible Metadata Tracking
por: Branson, Andrew, et al.
Publicado: (2014)

Boundary cells restrict dystroglycan trafficking to control basement membrane sliding during tissue remodeling
por: McClatchey, Shelly TH, et al.
Publicado: (2016)

Plant selection for ethnobotanical uses on the Amalfi Coast (Southern Italy)
por: Savo, V., et al.
Publicado: (2015)

Managing Evolving Business Workflows through the Capture of Descriptive Information
por: Gaspard, S, et al.
Publicado: (2003)

Activation of PPARγ in myeloid cells promotes lung cancer progression and metastasis
por: Nemenoff, Raphael
Publicado: (2012)

Designing Traceability into Big Data Systems
por: McClatchey, Richard, et al.
Publicado: (2015)

A Fault Tolerant, Dynamic and Low Latency BDII Architecture for Grids
por: Osman, Asif, et al.
Publicado: (2012)

Identification des équipements du LEP
por: Genier, Claude, et al.
Publicado: (1985)

SuperSILAC Quantitative Proteome Profiling of Murine Middle Ear Epithelial Cell Remodeling with NTHi
por: Val, Stéphanie, et al.
Publicado: (2016)

Managing Pan-European mammography images and data using a service oriented architecture
por: Amendolia, S R, et al.
Publicado: (2004)

Preclinical Remodeling of Human Prostate Cancer through the PTEN/AKT Pathway
por: De Velasco, Marco A., et al.
Publicado: (2012)

CRISTAL : A Practical Study in Designing Systems to Cope with Change
por: Branson, Andrew, et al.
Publicado: (2014)

The Reification of Patterns in the Design of Description-Driven Systems
por: Le Goff, J M, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_53tj5j3o7bl93r9b2p9v0d2ffe