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Evaluation of the potential of a simplified co-delivery system with oligodeoxynucleotides as a drug carrier for enhanced antitumor effect

BACKGROUND: We previously developed a simple effective system based on oligodeoxynucleotides with CGA repeating units (CGA-ODNs) for Dox and siRNA intracellular co-delivery. METHODS: In the present study, the in vitro cytotoxicity, gene transfection and in vivo safety of the co-delivery system were...

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Detalles Bibliográficos
Autores principales: Liu, Chunxi, Liu, Tingxian, Liu, Yongjun, Zhang, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916381/
https://www.ncbi.nlm.nih.gov/pubmed/29719392
http://dx.doi.org/10.2147/IJN.S155135