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Evaluation of the potential of a simplified co-delivery system with oligodeoxynucleotides as a drug carrier for enhanced antitumor effect
BACKGROUND: We previously developed a simple effective system based on oligodeoxynucleotides with CGA repeating units (CGA-ODNs) for Dox and siRNA intracellular co-delivery. METHODS: In the present study, the in vitro cytotoxicity, gene transfection and in vivo safety of the co-delivery system were...
Autores principales: | Liu, Chunxi, Liu, Tingxian, Liu, Yongjun, Zhang, Na |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916381/ https://www.ncbi.nlm.nih.gov/pubmed/29719392 http://dx.doi.org/10.2147/IJN.S155135 |
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