Critical Role of Flavin and Glutathione in Complex I–Mediated Bioenergetic Failure in Brain Ischemia/Reperfusion Injury

BACKGROUND AND PURPOSE—: Ischemic brain injury is characterized by 2 temporally distinct but interrelated phases: ischemia (primary energy failure) and reperfusion (secondary energy failure). Loss of cerebral blood flow leads to decreased oxygen levels and energy crisis in the ischemic area, initiat...

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Detalles Bibliográficos
Autores principales: Kahl, Anja, Stepanova, Anna, Konrad, Csaba, Anderson, Corey, Manfredi, Giovanni, Zhou, Ping, Iadecola, Costantino, Galkin, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Original Contributions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916474/
https://www.ncbi.nlm.nih.gov/pubmed/29643256
http://dx.doi.org/10.1161/STROKEAHA.117.019687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916474/
https://www.ncbi.nlm.nih.gov/pubmed/29643256
http://dx.doi.org/10.1161/STROKEAHA.117.019687

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