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Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo-Controlled, Multinational Study

BACKGROUND: Intra-articular corticosteroids relieve osteoarthritis pain, but rapid systemic absorption limits efficacy. FX006, a novel, microsphere-based, extended-release triamcinolone acetonide (TA) formulation, prolongs TA joint residence and reduces systemic exposure compared with standard TA cr...

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Detalles Bibliográficos
Autores principales: Conaghan, Philip G., Hunter, David J., Cohen, Stanley B., Kraus, Virginia B., Berenbaum, Francis, Lieberman, Jay R., Jones, Deryk G., Spitzer, Andrew I., Jevsevar, David S., Katz, Nathaniel P., Burgess, Diane J., Lufkin, Joelle, Johnson, James R., Bodick, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Journal of Bone and Joint Surgery, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916484/
https://www.ncbi.nlm.nih.gov/pubmed/29664853
http://dx.doi.org/10.2106/JBJS.17.00154