Long-term use of naldemedine in the treatment of opioid-induced constipation in patients with chronic noncancer pain: a randomized, double-blind, placebo-controlled phase 3 study

The long-term safety of naldemedine, a peripherally acting µ-opioid receptor antagonist, was evaluated in patients with opioid-induced constipation and chronic noncancer pain in a 52-week, randomized, double-blind, phase 3 study. Eligible adults who could be on a routine laxative regimen were random...

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Detalles Bibliográficos
Autores principales: Webster, Lynn R., Nalamachu, Srinivas, Morlion, Bart, Reddy, Jyotsna, Baba, Yuko, Yamada, Tadaaki, Arjona Ferreira, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916485/
https://www.ncbi.nlm.nih.gov/pubmed/29419653
http://dx.doi.org/10.1097/j.pain.0000000000001174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916485/
https://www.ncbi.nlm.nih.gov/pubmed/29419653
http://dx.doi.org/10.1097/j.pain.0000000000001174

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