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Effects of cell adhesion motif, fiber stiffness, and cyclic strain on tenocyte gene expression in a tendon mimetic fiber composite hydrogel

We recently developed a fiber composite consisting of tenocytes seeded onto discontinuous fibers embedded within a hydrogel, designed to mimic physiological tendon micromechanics of tension and shear. This study examined if cell adhesion peptide (DGEA or YRGDS), fiber modulus (50 or 1300 kPa) and/or...

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Detalles Bibliográficos
Autores principales: Patel, Dharmesh, Sharma, Sadhana, Screen, Hazel R.C., Bryant, Stephanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916510/
https://www.ncbi.nlm.nih.gov/pubmed/29601813
http://dx.doi.org/10.1016/j.bbrc.2018.03.203