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Principles that govern competition or co-existence in Rho-GTPase driven polarization

Rho-GTPases are master regulators of polarity establishment and cell morphology. Positive feedback enables concentration of Rho-GTPases into clusters at the cell cortex, from where they regulate the cytoskeleton. Different cell types reproducibly generate either one (e.g. the front of a migrating ce...

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Detalles Bibliográficos
Autores principales: Chiou, Jian-Geng, Ramirez, Samuel A., Elston, Timothy C., Witelski, Thomas P., Schaeffer, David G., Lew, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916526/
https://www.ncbi.nlm.nih.gov/pubmed/29649212
http://dx.doi.org/10.1371/journal.pcbi.1006095