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Principles that govern competition or co-existence in Rho-GTPase driven polarization
Rho-GTPases are master regulators of polarity establishment and cell morphology. Positive feedback enables concentration of Rho-GTPases into clusters at the cell cortex, from where they regulate the cytoskeleton. Different cell types reproducibly generate either one (e.g. the front of a migrating ce...
Autores principales: | Chiou, Jian-Geng, Ramirez, Samuel A., Elston, Timothy C., Witelski, Thomas P., Schaeffer, David G., Lew, Daniel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916526/ https://www.ncbi.nlm.nih.gov/pubmed/29649212 http://dx.doi.org/10.1371/journal.pcbi.1006095 |
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