Transmission genetics of drug-resistant hepatitis C virus

Antiviral development is plagued by drug resistance and genetic barriers to resistance are needed. For HIV and hepatitis C virus (HCV), combination therapy has proved life-saving. The targets of direct-acting antivirals for HCV infection are NS3/4A protease, NS5A phosphoprotein and NS5B polymerase....

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Detalles Bibliográficos
Autores principales: van Buuren, Nicholas, Tellinghuisen, Timothy L, Richardson, Christopher D, Kirkegaard, Karla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916564/
https://www.ncbi.nlm.nih.gov/pubmed/29589830
http://dx.doi.org/10.7554/eLife.32579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916564/
https://www.ncbi.nlm.nih.gov/pubmed/29589830
http://dx.doi.org/10.7554/eLife.32579

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