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Transmission genetics of drug-resistant hepatitis C virus
Antiviral development is plagued by drug resistance and genetic barriers to resistance are needed. For HIV and hepatitis C virus (HCV), combination therapy has proved life-saving. The targets of direct-acting antivirals for HCV infection are NS3/4A protease, NS5A phosphoprotein and NS5B polymerase....
Autores principales: | van Buuren, Nicholas, Tellinghuisen, Timothy L, Richardson, Christopher D, Kirkegaard, Karla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916564/ https://www.ncbi.nlm.nih.gov/pubmed/29589830 http://dx.doi.org/10.7554/eLife.32579 |
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