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Autophagy inhibition improves the cytotoxic effects of receptor tyrosine kinase inhibitors
BACKGROUND: A growing field of evidence suggests the involvement of oncogenic receptor tyrosine kinases (RTKs) in cell transformation. Deregulated activity of RTKs in tumors can determine disease progression and therapeutic responses in several types of cancer, including neuroblastoma (NB). Therefor...
Autores principales: | Aveic, Sanja, Pantile, Marcella, Polo, Pierfrancesco, Sidarovich, Viktoryia, De Mariano, Marilena, Quattrone, Alessandro, Longo, Luca, Tonini, Gian Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916832/ https://www.ncbi.nlm.nih.gov/pubmed/29713246 http://dx.doi.org/10.1186/s12935-018-0557-4 |
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