Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis

Replication of positive-strand RNA viruses [(+)RNA viruses] takes place in membrane-bound viral replication complexes (VRCs). Formation of VRCs requires virus-mediated manipulation of cellular lipid synthesis. Here, we report significantly enhanced brome mosaic virus (BMV) replication and much impro...

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Detalles Bibliográficos
Autores principales: Zhang, Zhenlu, He, Guijuan, Han, Gil-Soo, Zhang, Jiantao, Catanzaro, Nicholas, Diaz, Arturo, Wu, Zujian, Carman, George M., Xie, Lianhui, Wang, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916857/
https://www.ncbi.nlm.nih.gov/pubmed/29649282
http://dx.doi.org/10.1371/journal.ppat.1006988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916857/
https://www.ncbi.nlm.nih.gov/pubmed/29649282
http://dx.doi.org/10.1371/journal.ppat.1006988

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