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Host Pah1p phosphatidate phosphatase limits viral replication by regulating phospholipid synthesis
Replication of positive-strand RNA viruses [(+)RNA viruses] takes place in membrane-bound viral replication complexes (VRCs). Formation of VRCs requires virus-mediated manipulation of cellular lipid synthesis. Here, we report significantly enhanced brome mosaic virus (BMV) replication and much impro...
Autores principales: | Zhang, Zhenlu, He, Guijuan, Han, Gil-Soo, Zhang, Jiantao, Catanzaro, Nicholas, Diaz, Arturo, Wu, Zujian, Carman, George M., Xie, Lianhui, Wang, Xiaofeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916857/ https://www.ncbi.nlm.nih.gov/pubmed/29649282 http://dx.doi.org/10.1371/journal.ppat.1006988 |
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