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Inbreeding estimates in human populations: Applying new approaches to an admixed Brazilian isolate

The analysis of genomic data (~400,000 autosomal SNPs) enabled the reliable estimation of inbreeding levels in a sample of 541 individuals sampled from a highly admixed Brazilian population isolate (an African-derived quilombo in the State of São Paulo). To achieve this, different methods were appli...

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Detalles Bibliográficos
Autores principales: Lemes, Renan B., Nunes, Kelly, Carnavalli, Juliana E. P., Kimura, Lilian, Mingroni-Netto, Regina C., Meyer, Diogo, Otto, Paulo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916862/
https://www.ncbi.nlm.nih.gov/pubmed/29689090
http://dx.doi.org/10.1371/journal.pone.0196360