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Rigid and concave, 2,4-cis-substituted azetidine derivatives: A platform for asymmetric catalysis
A series of single enantiomer, 2,4-cis-disubstituted amino azetidines were synthesised and used as ligands for copper-catalysed Henry reactions of aldehydes with nitromethane. Optimisation of ligand substituents and the reaction conditions was conducted. The enantiomeric excess of the formed product...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916886/ https://www.ncbi.nlm.nih.gov/pubmed/29695806 http://dx.doi.org/10.1038/s41598-018-24784-3 |