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Molecular design of radiocopper-labelled Affibody molecules

The use of long-lived positron emitters (64)Cu or (61)Cu for labelling of Affibody molecules may improve breast cancer patients’ stratification for HER-targeted therapy. Previous animal studies have shown that the use of triaza chelators for (64)Cu labelling of synthetic Affibody molecules is subopt...

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Detalles Bibliográficos
Autores principales: Tolmachev, Vladimir, Grönroos, Tove J., Yim, Cheng-Bin, Garousi, Javad, Yue, Ying, Grimm, Sebastian, Rajander, Johan, Perols, Anna, Haaparanta-Solin, Merja, Solin, Olof, Ferdani, Riccardo, Orlova, Anna, Anderson, Carolyn J., Karlström, Amelie Eriksson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916907/
https://www.ncbi.nlm.nih.gov/pubmed/29695813
http://dx.doi.org/10.1038/s41598-018-24785-2