miR-9 upregulation leads to inhibition of erythropoiesis by repressing FoxO3

MicroRNAs (miRNAs) are emerging as critical regulators of normal and malignant hematopoiesis. In previous studies of acute myeloid leukemia miR-9 overexpression was commonly observed. Here, we show that ectopic expression of miR-9 in vitro and in vivo significantly blocks differentiation of erythroi...

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Detalles Bibliográficos
Autores principales: Zhang, Yunyuan, Li, Liping, Yu, Chunjie, Senyuk, Vitalyi, Li, Fuxing, Quigley, John G., Zhu, Tongyu, Qian, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916915/
https://www.ncbi.nlm.nih.gov/pubmed/29695725
http://dx.doi.org/10.1038/s41598-018-24628-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916915/
https://www.ncbi.nlm.nih.gov/pubmed/29695725
http://dx.doi.org/10.1038/s41598-018-24628-0

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