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miR-9 upregulation leads to inhibition of erythropoiesis by repressing FoxO3
MicroRNAs (miRNAs) are emerging as critical regulators of normal and malignant hematopoiesis. In previous studies of acute myeloid leukemia miR-9 overexpression was commonly observed. Here, we show that ectopic expression of miR-9 in vitro and in vivo significantly blocks differentiation of erythroi...
Autores principales: | Zhang, Yunyuan, Li, Liping, Yu, Chunjie, Senyuk, Vitalyi, Li, Fuxing, Quigley, John G., Zhu, Tongyu, Qian, Zhijian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916915/ https://www.ncbi.nlm.nih.gov/pubmed/29695725 http://dx.doi.org/10.1038/s41598-018-24628-0 |
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