Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner

Alterations in ERBB family members have been associated with many tumor malignancies. EGFR and ERBB2 have been extensively explored in clinical oncology and several drugs currently target them therapeutically. However, the significance of ERBB4 as a potential therapeutic target remains mostly unexpl...

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Detalles Bibliográficos
Autores principales: Rauf, Femina, Festa, Fernanda, Park, Jin G., Magee, Mitchell, Eaton, Seron, Rinaldi, Capria, Betanzos, Carlos Morales, Gonzalez-Malerva, Laura, LaBaer, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916919/
https://www.ncbi.nlm.nih.gov/pubmed/29398709
http://dx.doi.org/10.1038/s41388-017-0079-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916919/
https://www.ncbi.nlm.nih.gov/pubmed/29398709
http://dx.doi.org/10.1038/s41388-017-0079-x

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