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Ibrutinib inhibition of ERBB4 reduces cell growth in a WNT5A-dependent manner
Alterations in ERBB family members have been associated with many tumor malignancies. EGFR and ERBB2 have been extensively explored in clinical oncology and several drugs currently target them therapeutically. However, the significance of ERBB4 as a potential therapeutic target remains mostly unexpl...
Autores principales: | Rauf, Femina, Festa, Fernanda, Park, Jin G., Magee, Mitchell, Eaton, Seron, Rinaldi, Capria, Betanzos, Carlos Morales, Gonzalez-Malerva, Laura, LaBaer, Joshua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916919/ https://www.ncbi.nlm.nih.gov/pubmed/29398709 http://dx.doi.org/10.1038/s41388-017-0079-x |
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