Repression of let-7a cluster prevents adhesion of colorectal cancer cells by enforcing a mesenchymal phenotype in presence of liver inflammation

The liver is the most common site of metastasis in patients with colorectal cancer, and colorectal cancer liver metastasis (CRLM) is associated with poor rates of survival. However, CRLM occurs infrequently in livers exhibiting signs of hepatitis or cirrhosis, suggesting a role for inflammation in a...

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Detalles Bibliográficos
Autores principales: Cheng, Lipeng, Geng, Li, Dai, Binghua, Zheng, Tao, Fu, Jun, Qiao, Liang, Cai, Wenchang, Wang, Yue, Yang, Jiamei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916926/
https://www.ncbi.nlm.nih.gov/pubmed/29695839
http://dx.doi.org/10.1038/s41419-018-0477-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916926/
https://www.ncbi.nlm.nih.gov/pubmed/29695839
http://dx.doi.org/10.1038/s41419-018-0477-1

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