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Repression of let-7a cluster prevents adhesion of colorectal cancer cells by enforcing a mesenchymal phenotype in presence of liver inflammation
The liver is the most common site of metastasis in patients with colorectal cancer, and colorectal cancer liver metastasis (CRLM) is associated with poor rates of survival. However, CRLM occurs infrequently in livers exhibiting signs of hepatitis or cirrhosis, suggesting a role for inflammation in a...
Autores principales: | Cheng, Lipeng, Geng, Li, Dai, Binghua, Zheng, Tao, Fu, Jun, Qiao, Liang, Cai, Wenchang, Wang, Yue, Yang, Jiamei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916926/ https://www.ncbi.nlm.nih.gov/pubmed/29695839 http://dx.doi.org/10.1038/s41419-018-0477-1 |
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