Overactive autophagy is a pathological mechanism underlying premature suture ossification in nonsyndromic craniosynostosis

Nonsyndromic craniosynostosis (NSC) is the most common craniosynostosis with the primary defect being one or more fused sutures. In contrast to syndromic craniosynostosis, the etiopathogenesis of NSC is largely unknown. Here we show that autophagy, a major catabolic process required for the maintena...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiu, Shanshan, Wang, Jing, Huang, Siqi, Sun, Shouqing, Zhang, Zhen, Bao, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916928/
https://www.ncbi.nlm.nih.gov/pubmed/29695736
http://dx.doi.org/10.1038/s41598-018-24885-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916928/
https://www.ncbi.nlm.nih.gov/pubmed/29695736
http://dx.doi.org/10.1038/s41598-018-24885-z

Ejemplares similares