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Overactive autophagy is a pathological mechanism underlying premature suture ossification in nonsyndromic craniosynostosis
Nonsyndromic craniosynostosis (NSC) is the most common craniosynostosis with the primary defect being one or more fused sutures. In contrast to syndromic craniosynostosis, the etiopathogenesis of NSC is largely unknown. Here we show that autophagy, a major catabolic process required for the maintena...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916928/ https://www.ncbi.nlm.nih.gov/pubmed/29695736 http://dx.doi.org/10.1038/s41598-018-24885-z |