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A Genome-Wide Linkage Study for Chronic Obstructive Pulmonary Disease in a Dutch Genetic Isolate Identifies Novel Rare Candidate Variants

Chronic obstructive pulmonary disease (COPD) is a complex and heritable disease, associated with multiple genetic variants. Specific familial types of COPD may be explained by rare variants, which have not been widely studied. We aimed to discover rare genetic variants underlying COPD through a geno...

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Detalles Bibliográficos
Autores principales: Nedeljkovic, Ivana, Terzikhan, Natalie, Vonk, Judith M., van der Plaat, Diana A., Lahousse, Lies, van Diemen, Cleo C., Hobbs, Brian D., Qiao, Dandi, Cho, Michael H., Brusselle, Guy G., Postma, Dirkje S., Boezen, H. M., van Duijn, Cornelia M., Amin, Najaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916965/
https://www.ncbi.nlm.nih.gov/pubmed/29725345
http://dx.doi.org/10.3389/fgene.2018.00133