Humanized Mice Engrafted With Human HSC Only or HSC and Thymus Support Comparable HIV-1 Replication, Immunopathology, and Responses to ART and Immune Therapy

Immunodeficient mice reconstituted with human immune tissues and cells (humanized mice) are relevant and robust models for the study of HIV-1 infection, immunopathogenesis, and therapy. In this study, we performed a comprehensive comparison of human immune reconstitution and HIV-1 infection, immunop...

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Detalles Bibliográficos
Autores principales: Cheng, Liang, Ma, Jianping, Li, Guangming, Su, Lishan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916969/
https://www.ncbi.nlm.nih.gov/pubmed/29725337
http://dx.doi.org/10.3389/fimmu.2018.00817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916969/
https://www.ncbi.nlm.nih.gov/pubmed/29725337
http://dx.doi.org/10.3389/fimmu.2018.00817

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