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Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications

Tumor necrosis factor α (TNFα) is a pleiotropic cytokine which signals through TNF receptor 1 (TNFR1) and TNF receptor 2 (TNFR2). Emerging evidence has demonstrated that TNFR1 is ubiquitously expressed on almost all cells, while TNFR2 exhibits a limited expression, predominantly on regulatory T cell...

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Detalles Bibliográficos
Autores principales: Yang, Sujuan, Wang, Julie, Brand, David Douglass, Zheng, Song Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916970/
https://www.ncbi.nlm.nih.gov/pubmed/29725328
http://dx.doi.org/10.3389/fimmu.2018.00784