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Somatic BRCA1 mutations in clinically sporadic breast cancer with medullary histological features

BACKGROUND: The role of somatic BRCA1/2 gene mutations in breast cancer is getting increasing attention in view of hereditary disease. The medullary phenotype and triple negative intrinsic subtypes are often, but not exclusively encountered in BRCA1 germline mutated breast cancer, whilst for BRCA2,...

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Detalles Bibliográficos
Autores principales: Rechsteiner, Markus, Dedes, Konstantin, Fink, Daniel, Pestalozzi, Bernhard, Sobottka, Bettina, Moch, Holger, Wild, Peter, Varga, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916977/
https://www.ncbi.nlm.nih.gov/pubmed/29453630
http://dx.doi.org/10.1007/s00432-018-2609-5