Dacarbazine depletes the ovarian reserve in mice and depletion is enhanced with age

Dacarbazine is commonly administered for the treatment of cancers prevalent in reproductive age females. However, investigations of off-target effects of dacarbazine on the ovary are limited. We assessed the impact of dacarbazine on the ovarian reserve of primordial follicles, essential for fertilit...

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Detalles Bibliográficos
Autores principales: Winship, Amy L., Bakai, Monika, Sarma, Urooza, Liew, Seng H., Hutt, Karla J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917018/
https://www.ncbi.nlm.nih.gov/pubmed/29695822
http://dx.doi.org/10.1038/s41598-018-24960-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917018/
https://www.ncbi.nlm.nih.gov/pubmed/29695822
http://dx.doi.org/10.1038/s41598-018-24960-5

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