Differential Hyperphosphorylation of Tau-S199, -T231 and -S396 in Organotypic Brain Slices of Alzheimer Mice. A Model to Study Early Tau Hyperphosphorylation Using Okadaic Acid

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder of the brain, characterized by extracellular aggregation of beta-amyloid (Aβ) and hyperphosphorylation of tau causing intraneuronal neurofibrillary tangles (NFTs). There is urgent need to study the interactions between Aβ and tau,...

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Detalles Bibliográficos
Autores principales: Foidl, Bettina M., Humpel, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917035/
https://www.ncbi.nlm.nih.gov/pubmed/29725295
http://dx.doi.org/10.3389/fnagi.2018.00113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917035/
https://www.ncbi.nlm.nih.gov/pubmed/29725295
http://dx.doi.org/10.3389/fnagi.2018.00113

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