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The Mu.Ta.Lig. Chemotheca: A Community-Populated Molecular Database for Multi-Target Ligands Identification and Compound-Repurposing

For every lead compound developed in medicinal chemistry research, numerous other inactive or less active candidates are synthetized/isolated and tested. The majority of these compounds will not be selected for further development due to a sub-optimal pharmacological profile. However, some poorly ac...

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Detalles Bibliográficos
Autores principales: Ortuso, Francesco, Bagetta, Donatella, Maruca, Annalisa, Talarico, Carmine, Bolognesi, Maria L., Haider, Norbert, Borges, Fernanda, Bryant, Sharon, Langer, Thierry, Senderowitz, Hanoch, Alcaro, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917039/
https://www.ncbi.nlm.nih.gov/pubmed/29725591
http://dx.doi.org/10.3389/fchem.2018.00130