Salidroside Promotes the Pathological α-Synuclein Clearance Through Ubiquitin-Proteasome System in SH-SY5Y Cells

Parkinson’s disease (PD) is characterized by the loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc) and the presence of Lewy bodies (LBs) in the surviving SNc neurons. LBs formation is caused by the accumulation of α-synuclein (α-syn) or phosphorylated α-syn at serine-129...

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Detalles Bibliográficos
Autores principales: Li, Tao, Feng, Yang, Yang, Ruixin, Wu, Leitao, Li, Ruru, Huang, Lu, Yang, Qian, Chen, Jianzong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917065/
https://www.ncbi.nlm.nih.gov/pubmed/29725300
http://dx.doi.org/10.3389/fphar.2018.00377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917065/
https://www.ncbi.nlm.nih.gov/pubmed/29725300
http://dx.doi.org/10.3389/fphar.2018.00377

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